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Total 135 results found since Jan 2013.
Corrigendum to "Genotype prevalence and age distribution of human papillomavirus from infection to cervical cancer in Japanese women: A systematic review and meta-analysis" Vaccine 40(41) (2022) 5971-5996
Vaccine. 2023 Sep 1:S0264-410X(23)00787-9. doi: 10.1016/j.vaccine.2023.06.084. Online ahead of print.NO ABSTRACTPMID:37659892 | DOI:10.1016/j.vaccine.2023.06.084
Source: Cancer Control - September 2, 2023 Category: Cancer & Oncology Authors: Matthew Palmer Kota Katanoda Eiko Saito Cecilia Acuti Martellucci Shiori Tanaka Sayaka Ikeda Haruka Sakamoto Dorothy Machalek Julia M L Brotherton Jane S Hocking Source Type: research
A questionnaire survey on the prevention of HPV infection among females and males who came of age in Japan under various scenarios of HPV vaccine recommendation
Hum Vaccin Immunother. 2023 Aug 1;19(2):2229222. doi: 10.1080/21645515.2023.2229222.ABSTRACTThe Japanese Ministry of Health, Labor and Welfare (MHLW) temporarily suspended recommendation for HPV vaccinations for girls in June 2013. It resumed its recommendation in November 2021. To compensate for eight years of lost overage, a 'catch-up HPV vaccination' program began in April 2022. To determine intervention needs in regards to HPV vaccine hesitancy, from October 13 2021 to April 31 2022, we surveyed 12-28 year-old vaccine-eligible males and females (281 males, 583 females). We investigated the gender and 'vaccine generatio...
Source: Cancer Control - July 18, 2023 Category: Cancer & Oncology Authors: Tatsuki Ishimoto Asami Yagi Kanon Nakajima Natsume Okamoto Erika Yukimitsu Miyo Kawasaki Yuzuki Kawae Shuma Hayasaka Yutaka Ueda Tadashi Kimura Source Type: research
Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues.
Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease
https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/
With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT.
Age-Related Dysfunction of Water Homeostasis
https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/
Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechani...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Updated Guidance Regarding The Risk ofAllergic Reactions to COVID-19 Vaccines and Recommended Evaluation and Management: A GRADE Assessment, and International Consensus Approach
J Allergy Clin Immunol. 2023 Jun 7:S0091-6749(23)00746-7. doi: 10.1016/j.jaci.2023.05.019. Online ahead of print.ABSTRACTThis guidance updates 2021 GRADE recomendations regarding immediate allergic reactions following COVID-19 vaccines and addresses re-vaccinating individuals with 1st dose allergic reactions and allergy testing to determine re-vaccination outcomes. Recent meta-analyses assessed the incidence of severe allergic reactions to initial COVID-19 vaccination, risk of mRNA-COVID-19 re-vaccination after an initial reaction, and diagnostic accuracy of COVID-19 vaccine and vaccine excipient testing in predicting reac...
Source: Clinical Lung Cancer - June 9, 2023 Category: Cancer & Oncology Authors: Matthew Greenhawt Timothy E Dribin Elissa M Abrams Marcus Shaker Derek K Chu David Bk Golden Cem Akin Akterini Anagnostou Faisal ALMuhizi Waleed Alqurashi Peter Arkwright James L Baldwin Aleena Banerji Philippe B égin Moshe Ben-Shoshan Jonathan Bernstein Source Type: research
Post-COVID Health-related Quality of Life and Somatic Symptoms: A National Survey in Japan
Am J Med Sci. 2023 Apr 27:S0002-9629(23)01165-5. doi: 10.1016/j.amjms.2023.04.018. Online ahead of print.ABSTRACTBACKGROUND: The characteristics and risk factors of post-COVID-19 condition affecting health-related quality of life and the symptom burden are unclear.METHODS: The present, cross-sectional study used the JASTIS (Japan Society and New Tobacco Internet Survey) database. EQ-5D-5L and Somatic Symptom Scale-8 were used to assess health-related quality of life and somatic symptoms, respectively. The participants were classified into a no-COVID-19, COVID-19 not requiring oxygen therapy or COVID-19 requiring oxygen the...
Source: Cancer Control - April 29, 2023 Category: Cancer & Oncology Authors: Kazuhiro Kamata Hitoshi Honda Yasuharu Tokuda Akane Takamatsu Kiyosu Taniguchi Kenji Shibuya Takahiro Tabuchi Source Type: research
Live-attenuated Japanese encephalitis virus inhibits glioblastoma growth and elicits potent antitumor immunity
In this study, we investigated the safety of a live attenuated Japanese encephalitis vaccine strain (JEV-LAV) virus as an oncolytic virus for intracerebral injection in mice. We infected different GBM cell lines with JEV-LAV to investigate whether it had growth inhibitory effects on GBM cell lines in vitro. We used two models for evaluating the effect of JEV-LAV on GBM growth in mice. We investigated the antitumor immune mechanism of JEV-LAV through flow cytometry and immunohistochemistry. We explored the possibility of combining JEV-LAV with PD-L1 blocking therapy. This work suggested that JEV-LAV had oncolytic activity a...
Source: Cancer Control - April 28, 2023 Category: Cancer & Oncology Authors: Zhongbing Qi Jing Zhao Yuhua Li Bin Zhang Shichuan Hu Yanwei Chen Jinhu Ma Yongheng Shu Yunmeng Wang Ping Cheng Source Type: research
Future perspectives of emerging novel drug targets and immunotherapies to control drug addiction
This article's main highlight is discussing the drug targets of SUDs and their associated mechanisms. Importantly, we have also discussed the scope of prophylactic measures to eliminate drug dependence.PMID:37099943 | DOI:10.1016/j.intimp.2023.110210
Source: International Immunopharmacology - April 26, 2023 Category: Allergy & Immunology Authors: Jonaid Ahmad Malik Javed N Agrewala Source Type: research
Impact of COVID-19 Pandemic on the Influenza Vaccination and Predictors of Influenza Vaccination in Japan: A Cross-sectional Study
CONCLUSIONS: It is crucial to use predictors of influenza vaccination, such as how to use the media, for promoting a more widespread influenza vaccination uptake. The results of this study may be helpful in improving influenza vaccination rates, which could reduce the burden on health care services during outbreaks of influenza and COVID-19.PMID:37097180 | DOI:10.1097/PHH.0000000000001755
Source: Cancer Control - April 25, 2023 Category: Cancer & Oncology Authors: Kensaku Shojima Taiichiro Kobayashi Takahiro Tabuchi Source Type: research
Duration of influenza vaccine effectiveness in the elderly in Japan: A retrospective cohort study using large-scale population-based registry data
CONCLUSIONS: Our study identified moderate vaccine effectiveness in preventing the incidence of influenza in the Japanese elderly. Vaccine effectiveness showed a trend of gradual attenuation. Clinicians should suspect influenza infection even in those vaccinated, especially in elderly individuals who had received vaccination more than 4 or 5 months previously.PMID:37045684 | DOI:10.1016/j.vaccine.2023.03.066
Source: Vaccine - April 12, 2023 Category: Allergy & Immunology Authors: Kohei Uemura Sachiko Ono Nobuaki Michihata Hayato Yamana Hideo Yasunaga Source Type: research
Patterns of HPV vaccine hesitancy among catch-up generations in Japan: A descriptive study
CONCLUSION: HPV vaccine awareness promotion strategies must be based on the characteristics of each group and the different distributions of sociodemographic factors.PMID:37024410 | DOI:10.1016/j.vaccine.2023.03.061
Source: Vaccine - April 6, 2023 Category: Allergy & Immunology Authors: Masaki Machida Shigeru Inoue Source Type: research
